Publications by authors named "Alessio Cocco"
Article Synopsis
- Treatment-Resistant Depression (TRD) affects about 30% of people with Major Depressive Disorder, and a new nasal spray called Esketamine (ESK-NS) has been approved to help treat it when combined with certain medications.
- Researchers wanted to see if combining Vortioxetine, another antidepressant, with ESK-NS was just as good or better than the usual treatment.
- The results showed that the Vortioxetine and ESK-NS combo worked well to reduce depression and had fewer side effects, suggesting it could be a better option, but more research is needed to be sure.
Overcoming treatment-resistant depression with machine-learning based tools: a study protocol combining EEG and clinical data to personalize glutamatergic and brain stimulation interventions (SelecTool Project).
Front Psychiatry
July 2024
Article Synopsis
- Treatment-Resistant Depression (TRD) is a significant health issue that's hard to tackle due to its complex nature and varied symptoms, prompting the need for better treatment strategies.
- The SelecTool Project is introduced as a computational tool that combines clinical data, EEG, and blood biomarkers using machine learning to personalize TRD treatments, specifically focusing on esketamine nasal spray and accelerated repetitive Transcranial Magnetic Stimulation.
- The project involves two main phases: first, a study with 100 TRD subjects to evaluate the effectiveness of treatments, and then training the tool to assist in managing an additional 20 subjects, ultimately aiming to improve TRD treatment outcomes through advanced data analysis.
Morphology and ultrastructure of the infrabuccal pocket in Strumigenys ants.
Arthropod Struct Dev
May 2022
The morphology of the infrabuccal pocket has been studied with light and electron microscopy (SEM, TEM) in 19 species of Strumigenys ants. The structural organization is similar in workers, queens and males, and supports the involvement of the pocket in the filtration of food particles before they can enter the digestive tract. A carpet of posteriorly oriented bristle hairs on the hypopharynx first guide ingested food into the pocket, where large solid particles are compacted into a pellet that will be regurgitated.
View Article and Find Full Text PDFThe Effects of "VelaMente?!" Project on Social Functioning of People With Severe Psychosocial Disabilities.
Clin Pract Epidemiol Ment Health
November 2017
Introduction: Physical activity helps to improve several clinical outcomes of people with severe psychosocial disabilities. The aims of this study were; 1) to assess the efficacy of a psychosocial rehabilitative intervention focused on sailing in a crew on: a) social functioning; b) severity of the psychosocial disability; c) general functioning; d) dysregulation of biorhythms of people with severe psychosocial disabilities, and 2) to evaluate the attenders' satisfaction about the project.
Methods: A randomized waitlist controlled trial with parallel groups was carried out involving 51 people with severe psychosocial disabilities.
Introduction: It has been proposed that sailing can improve quality of life, personal and social skills of people with severe psychosocial disabilities. This study aimed to assess the efficacy of a psychosocial rehabilitative intervention focused on sailing on quality of life, self-efficacy and sense of coherence in people with severe psychosocial disabilities.
Methods: The study was a randomized, with parallel groups, waiting-list controlled trial.