Publications by authors named "Alessio Bocchetti"
The risk of gastric and/or esophageal cancers after bariatric surgery has been previously discussed in literature. A systematic review was performed to identify articles published between June 2012 and December 2018 reporting new cases of esophageal or gastric cancer not included in previous systematic reviews. Ten gastric malignancies, 28 esophageal cancers, and 2 gastro-intestinal stromal tumors (GIST) were identified.
View Article and Find Full Text PDFBackground: To understand the role of ghrelin in the mechanism of action of laparoscopic sleeve gastrectomy (LSG), a prospective cohort case-control study to assess the expression of ghrelin-producing cells (GPC) in two groups of patients was designed.
Methods: Specimens of resected stomach from 26 obese patients who underwent LSG (group A), were compared by immunohistochemistry to control stomach samples from 26 non-obese patients (group B) resected for other pathologies or during autopsy; (GIST: 6 cases, inflammatory diseases: 4 cases, post-mortem autopsy cases with stomachs from healthy persons victims of traumatic accidents: 16 cases). Immunohistochemistry investigation was performed with the use of Ventana Benchmark ultra, anti-ghrelin antibody NOVUS, mouse monoclonal 2F4, diluted at 1:100.
Background: Laparoscopic sleeve gastrectomy (LSG) represents the most performed bariatric surgical procedure worldwide. Morbid Overweight in elderly patients is becoming a significant health problem even in Italy. As well as in younger age groups, bariatric surgery could be indicated even in this subset of patients.
View Article and Find Full Text PDFArticle Synopsis
- Obesity is increasingly prevalent among individuals over 60, and Intragastric Balloon (IGB) treatment is an effective method for achieving significant weight loss and improving related health issues in this age group.
- A study of 225 patients, including 12 elderly individuals, found that IGB treatment resulted in a 31.4% excess weight loss on average, though it also revealed a higher rate of complications in older patients compared to younger ones.
- While IGB treatment is generally safe and effective for elderly patients, complications can occur, such as esophagitis and gastric perforation, making close follow-up and prompt investigation of any issues essential.