Publications by authors named "Alessio Basciu"

Article Synopsis
  • This study examines the long-term outcomes of minimally invasive mitral valve repair (MIMVR) in patients with degenerative mitral regurgitation, focusing on survival rates and recurrence of heart issues.
  • It finds that all primary repair techniques (quadrangular resection, edge-to-edge repair, and artificial chordae implantation) show high survival rates over 1, 10, and 20 years, indicating the procedures are beneficial long-term.
  • The study highlights that the quadrangular resection and edge-to-edge techniques have better outcomes for preventing moderate mitral regurgitation recurrence compared to artificial chordae, with low re-operation rates across all methods and pre-discharge residual issues predicting future repair failures.
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Article Synopsis
  • Infective endocarditis (IE) remains a serious and potentially life-threatening condition, even with advancements in diagnosis and treatment, largely influenced by demographic changes and the use of medical devices.
  • Recent guidelines from organizations like the ESC and AHA have clarified the diagnostic and therapeutic approaches to IE, emphasizing the importance of timely surgical intervention for about half of those affected to prevent complications like heart failure and embolism.
  • The guidelines also stress the need for a specialized endocarditis team to manage various systemic complications that can impact surgical timing and patient outcomes, while considering factors such as the type of endocarditis and anatomical challenges during surgery.
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Ventricular assist devices (VADs) are considered the standard of care for end-stage heart failure (HF) patients. Despite increasing confidence in the technology, evidence data, endorsement by scientific societies and guidelines, the number of implants reached a steady state and is not increasing at the expected pace. This is most likely related to complications that are still burdening the technology and consequently excluding the most needy, ill, and fragile population.

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Article Synopsis
  • - The study examined whether performing additional cusp repair during valve-sparing aortic root replacement impacts mid-term results, focusing on patients with bicuspid (BAV) and tricuspid aortic valve (TAV).
  • - Out of 157 patients, only 19% had BAV, and it was found that those who received cusp repair had a significantly higher rate of reoperation compared to those who did not.
  • - Overall, cusp repair increased reoperation risk in BAV patients, but it did not affect TAV patients; the authors advise caution when using this technique for asymmetric BAV cases.
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Objective: To shed light on contemporary results of open total aortic arch surgery, we undertook a systematic review to identify all reports on this procedure published in the last 10 years.

Methods: Extensive electronic literature search was undertaken to identify all published articles from 2004 to 2014 that provided results on total aortic arch replacement. According to inclusion and exclusion criteria, 21 relevant studies were selected and meta-analyzed to assess outcomes.

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Article Synopsis
  • A study compared hybrid and conventional treatments for acute type A aortic dissection to assess outcomes like mortality and complications.
  • Seven studies were analyzed, involving 967 patients, revealing no significant differences in mortality or neurological deficits between the two treatment methods.
  • However, the hybrid method showed a higher rate of false lumen thrombosis and a lower need for follow-up surgeries, particularly when using the frozen elephant trunk technique.
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Aims: Aortic valve-sparing operations are nowadays considered safe and reliable procedures in terms of mid-term and long-term results. Although surgical techniques regarding the modality of grafts' implantation have been properly addressed, the modality of cusp repair, when needed, is still open to debate. We sought to review the literature to try to shed light on when the cusp repair is required and how it should be performed.

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Background: The Synergy system, a miniature partial circulatory support device, is implanted by an off-pump, minimally invasive surgical approach. The system has been optimized to improve performance in an EU clinical trial for chronic ambulatory heart failure. This therefore offers the possibility of treating elderly chronic heart failure patients who might not usually be considered for long-term circulatory support.

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Aortic false aneurysm is a rare complication after cardiac surgery. In recent years, improved results have been reported in regard to the surgical management of these high-risk lesions. We retrospectively examined 28 consecutive cases (in 27 patients) of postsurgical aortic false aneurysm diagnosed at our institution from May 1999 through December 2011.

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Aim: Minimally invasive coronary artery bypass (MIDCAB) allows revascularization of the left anterior descending coronary (LAD) artery through a less traumatic surgical approach. However, the procedure is technically challenging and concern still exists, mainly based on graft patency. The purpose of this study is to critically evaluate short and long-term benefits of this surgical treatment.

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A 67-year-old man presented to our hospital with massive mitral and aortic valve prosthetic endocarditis 2 months after transcatheter percutaneous closure of a mitral paravalvular leak with an Amplatzer duct occluder device (AGA Medical Corp, Plymouth MN). He underwent successful reoperation for valve prosthesis replacement and reconstruction of the anterior fibrous trigone. Although transcatheter treatment of periprosthetic valve defects has been shown to be feasible, follow-up data are still limited.

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Postsurgical aortic false aneurysm occurs in less than 0.5% of all cardiac surgical cases and its management is a challenge in terms of preoperative evaluation and surgical approach. Although infections are well recognized as risk factors, technical aspects of a previous operation may have a role in pseudoaneurysm formation.

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An otherwise healthy 47-year-old man presented to the emergency department in cardiogenic shock after suffering a massive myocardial infarction due to left main occlusion. He was initially supported by extracorporeal membrane oxygenation and subsequently was converted to paracorporeal support with a Levitronix left ventricular assist device. He experienced multiple postoperative complications including renal failure, respiratory failure, retroperitoneal hematoma requiring suspension of anticoagulation, and fungal bloodstream infection precluding transition to an implantable device.

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Aortic valve reimplantation has been shown to be a safe procedure. However, evidences of durability in bicuspid aortic valves (BAVs) are limited in the literature. Between 2002 and 2011, 132 patients (mean age 61 ± 12 years) underwent aortic valve reimplantation.

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Conversion to surgical aortic valve replacement (AVR) has been described as a complication following transcatheter aortic valve implantation. This complication occurs in up to 8% of cases and, to the best of our knowledge, preoperative data and surgical outcomes of such patients have not been properly evaluated. Mild paraprosthetic regurgitation is commonly observed after transcatheter aortic valve implantation and usually leads to a benign clinical course.

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Objectives: Reimplantation valve-sparing aortic root replacement has been increasingly performed with improving perioperative and mid-term results. The success of this operation primarily depends on preserving the highly sophisticated dynamic function of the aortic valve by recreating an anatomical three-dimensional configuration similar to the normal aortic root, thus minimizing the mechanical stress and strain on the cusps. Over the years several techniques have been proposed to reproduce the sinuses of Valsalva.

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