Publications by authors named "Alessia Carli"

Article Synopsis
  • The study evaluated neonatal seizures (NS) in a tertiary neonatal intensive care unit, focusing on their epidemiology, seizure types, EEG findings, and underlying causes over a period from 2009 to 2022.
  • Out of 91,253 neonates, 145 experienced NS, with a notable incidence of 1.2 per 1,000 live births, revealing a higher genetic contribution (26.2%) and lower hypoxic-ischemic encephalopathy (HIE) rates (23.4%) compared to earlier research.
  • Findings indicated that seizure types and EEG patterns were crucial in determining the etiology, with specific associations noted between seizure characteristics and conditions like preterm birth, infections, vascular issues,
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Vaccination against an airborne pathogen is very effective if it induces also the development of mucosal antibodies that can protect against infection. The mRNA-based vaccine-encoding SARS-CoV-2 full-length spike protein (BNT162b2, Pfizer/BioNTech) protects also against infection despite being administered systemically. Here, we show that upon vaccination, cognate IgG molecules are also found in the saliva and are more abundant in SARS-CoV-2 previously exposed subjects, paralleling the development of plasma IgG.

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Background And Aims: The SARS-CoV-2 pandemic has overwhelmed the treatment capacity of the health care systems during the highest viral diffusion rate. Patients reaching the emergency department had to be either hospitalized (inpatients) or discharged (outpatients). Still, the decision was taken based on the individual assessment of the actual clinical condition, without specific biomarkers to predict future improvement or deterioration, and discharged patients often returned to the hospital for aggravation of their condition.

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