Publications by authors named "Alessia Bellasame"
Int J Mol Sci
September 2024
Article Synopsis
- Glioblastoma multiforme (GBM) releases extracellular vesicles (EVs) that can transfer aggressive traits to other cells, making the study of these vesicles crucial for understanding tumor behavior.
- * EV proteins are being investigated to find new biomarkers and targets for treatment, with proteomic studies primarily using "bottom-up" mass spectrometry on EVs from GBM cells and patient fluids.
- * Despite identifying many dysregulated proteins, clinical translation is challenging due to inconsistent EV isolation methods and proteome analysis, highlighting the need for standardized techniques and exploring protein mutations to improve GBM therapies.*
