4-Connected azabicyclo[5.3.0]decane Smac mimetics-Zn chelators as dual action antitumoral agents.

Putative dual action compounds (DACs 3a-d) based on azabicyclo[5.3.0]decane (ABD) Smac mimetic scaffolds linked to Zn-chelating 2,2'-dipicolylamine (DPA) through their 4 position are reported and characterized.