Publications by authors named "Alessandro Saeed Querner"
Background: By being highly involved in the tumor evolution and disease progression of small cell lung cancer (SCLC), Myc family members (C-Myc, L-Myc, and N-Myc) might represent promising targetable molecules. Our aim was to investigate the expression pattern and prognostic relevance of these oncogenic proteins in an international cohort of surgically resected SCLC tumors.
Methods: Clinicopathological data and surgically resected tissue specimens from 104 SCLC patients were collected from two collaborating European institutes.
Article Synopsis
- * Researchers analyzed data from 101 patients who had surgery for SCLC from 2000 to 2019, finding that an LMR greater than 2.50 was linked to significantly better overall survival and disease-free survival rates.
- * The study concludes that higher preoperative LMR predicts improved outcomes for SCLC surgical patients, suggesting the need for further research to fully understand LMR's implications in this context.