Neuraminidase alters red blood cells in sepsis.

Objective: To investigate the influence of neuraminidase, an enzyme that cleaves sialic acid from the red blood cell (RBC) membrane, on RBC shape and biochemistry in critically ill patients.

Design: Prospective, observational study and in vitro laboratory study.

Setting: A 31-bed medico-surgical department of intensive care and a university-affiliated cell biology laboratory.

Comparison of parecoxib and proparacetamol in endoscopic nasal surgery patients.

Purpose: The aim of the study was to compare the efficacy of parecoxib for postoperative analgesia after endoscopic turbinate and sinus surgery with the prodrug of acetaminophen, proparacetamol.

Materials And Methods: Fifty American Society of Anesthesiology (ASA) physical status I-II patients, receiving functional endoscopic sinus surgery (FESS) and endoscopic turbinectomy, were investigated in a prospective, randomized, double-blind manner. After local infiltration with 1% mepivacaine, patients were randomly allocated to receive intravenous (i.