Feasibility of cardiopulmonary exercise test in an athlete who underwent total laringectomy.

We report the case of an athlete who, despite facing the challenges of laryngectomy, underwent a comprehensive cardiopulmonary exercise test to assess both his ability to participate in sports and his cardiopulmonary fitness. We not only highlight the individualized approach to sports assessment in a challenging medical context but also emphasize the feasibility of employing cardiopulmonary testing in evaluating subjects in unusual settings.

Exploring the Prognostic Performance of MECKI Score in Heart Failure Patients with Non-Valvular Atrial Fibrillation Treated with Edoxaban.

Introduction: Risk stratification in heart failure (HF) is essential for clinical and therapeutic management. The Metabolic Exercise test data combined with Cardiac and Kidney Indexes (MECKI) score is a validated prognostic model for assessing cardiovascular risk in HF patients with reduced ejection fraction (HFrEF). From the validation of the score, the prevalence of HF patients treated with direct oral anticoagulants (DOACs), such as edoxaban, for non-valvular atrial fibrillation (NVAF) has been increasing in recent years.

Inverse finite element characterization of the human myometrium derived from uniaxial compression experiments.

The low strain-rate behavior of the human myometrium under compression was determined. To this end, uniaxial, unconstrained compression experiments were conducted on a total of 25 samples from three excised human uteri at strain rates between 0.001 s(-1) and 0.

The mechanical response of human liver and its relation to histology: an in vivo study.

The mechanical response of human liver is characterized in vivo by means of intra-operative aspiration experiments. Mechanical characterization is combined with histological evaluation of liver tissue biopsies obtained from the resected liver at the site of mechanical testing. This procedure enables a quantitative analysis of the correlation between mechanical response and tissue micro-structure of normal and diseased liver.

In vivo characterization of the mechanics of human uterine cervices.

The uterine cervix has to provide mechanical resistance to ensure a normal development of the fetus. This is guaranteed by the composition of its extracellular matrix, which functions as a fiber-reinforced composite. At term a complex remodeling process allows the cervical canal to open for birth.

Mechanical properties of the human uterine cervix: an in vivo study.

Experimental results of in vivo measurements to characterize the mechanical behaviour of human uterine cervices are documented. Aspiration experiments were performed on eight uteri in vivo, before vaginal/abdominal hysterectomy, and four uteri were also tested ex vivo, approximately 1.5h after extraction.

Evaluation of the mechanical properties of human liver and kidney through aspiration experiments.

A proper mechanical characterization of soft biological tissues of the human body has a strong impact on several medical applications such as surgical planning, virtual reality simulators, trauma research, and for diagnostic purposes. Adequate experimental data are needed to describe quantitatively the mechanical behaviour of those organs. We present a technique for the acquisition of such data from soft tissues and its post processing, based on a continuum mechanics approach, to determine some parameters of the tissue's mechanical properties.