Mortality and risk factors for invasive fungal infections after the implementation of a fluconazole prophylaxis protocol in very low birth weight infants.

Unlabelled: Fungal infections are a common cause of late-onset sepsis in very low birth weight infants and can impact mortality and morbidity. The purpose of this study is to determine the impact of systemic fluconazole prophylaxis in the prevalence of fungemia.

Methods: Subjects included 402 very low birth weight premature infants with birth weights between 500 and 1,250 grams admitted to the University Pediatric Hospital NICU over a six year period.

Oseltamivir therapy in two low birth-weight premature infants born to women with H1N1 influenza.

The influenza A (H1N1) virus may cause severe illness in humans, especially children less than two years of age. The neuraminidase enzyme inhibitor, oseltamivir, is a potent medication for the management of patients with this infection. Minimal information exists regarding the immediate and long term effects of oseltamivir therapy in low birth weight premature infants born to mothers with this viral illness.