Publications by authors named "Alessandro Iacono"
Article Synopsis
- Dabrafenib plus trametinib shows strong effectiveness and manageable side effects for patients with -mutant glioma.
- There is a notable case of a patient with recurrent anaplastic pleomorphic xanthoastrocytoma who had a complete and lasting response to this treatment.
- Continued development of targeted therapies and treatment strategies is expected to enhance personalized care for high-grade glioma patients, ultimately improving their outcomes.
Low grade gliomas (LGGs) of pineal region are usually difficult to remove and they frequently relapse or progress after front line chemotherapy. Bevacizumab-Irinotecan (BEVIRI) combination has been successfully attempted in children with recurrent LGGs, in most cases not previously irradiated. The efficacy of bevacizumab has also been described in radiation necrosis.
View Article and Find Full Text PDFObjective: To determine the expression of HECA-452 epitope in mycosis fungoides (MF), assess whether its expression increases in relapsed MF compared with nonrelapsed MF and determine the potential prognostic relevance of HECA-452 expression.
Study Design: HECA-452 expression was evaluated by immunohistochemistry in a consecutive series of 20 MF. In all patients we evaluated the disease-free survival rate according to HECA-452 expression in a univariate analysis.
Brunner's gland adenoma (BGA) is a very rare benign tumour of the duodenum, which is usually asymptomatic and discovered incidentally at endoscopy. Occasionally, this lesion may be large, causing upper gastrointestinal haemorrhage or intestinal obstruction. The case had a large Brunner's gland adenoma, presenting melena that was managed by endoscopic excision.
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