Publications by authors named "Alessandro Fernandes Valdez"
Unveiling the Morphostructural Plasticity of Zoonotic Sporotrichosis Fungal Strains: Possible Implications for Virulence and Pathogenicity.
Dario Corrêa-Junior Iara Bastos de Andrade Vinicius Alves Igor Avellar-Moura Vanessa Brito de Souza Rabello Alessandro Fernandes Valdez
J Fungi (Basel)
June 2023
Article Synopsis
- Sporotrichosis is a fungal infection primarily caused by certain species, particularly in Latin America, but the factors that contribute to its virulence remain largely unclear.
- This study focused on analyzing various characteristics of the fungus responsible for sporotrichosis, such as cell surface traits, biofilm formation, and other properties linked to virulence, including lipid bodies and chitin.
- Findings indicated that key features like chitin, lipid bodies, and conductance are significant for fungal virulence, with specific relationships identified between hydrophobicity, biomass production, and extracellular matrix formation.
This study aimed to investigate the effects of cyclosporine on the morphology, cell wall structure, and secretion characteristics of . The minimum inhibitory concentration (MIC) of cyclosporine was found to be 2 µM (2.4 µg/mL) for the H99 strain.
View Article and Find Full Text PDF