Quantitative investigation of desmoplasia as a prognostic indicator in colorectal cancer.

Background: The role of desmoplastic reaction (DR) in colorectal cancer invasion is still an open question. The presence of fibrous connective tissue may represent a barrier against cancer diffusion or a stroma to build up and support the tumor. Aims of the present study were to evaluate the influence of DR on long-term survival and to validate a reliable quantitative method to measure the desmoplastic tissue.

Retrograde parotidectomy for pleomorphic adenoma of the parotid gland: a conservative and effective approach.

To compare the extensiveness and the effectiveness of anterograde and retrograde dissections in superficial parotidectomy for pleomorphic adenoma of the parotid gland, a review of medical records and pathology reports of consecutive patients who underwent superficial parotidectomy has been performed. The sizes of the overall pathologic specimen, the tumor within the specimen, and the normal parotid tissue obtained by anterograde and retrograde approaches have been compared. Mann-Whitney and chi tests have been used to reveal significant differences.

Silent colon carcinoma presenting as a hepatic abscess.

Penetration and abscess formation in an adjacent parenchymal organ as presentation of a colon cancer is very uncommon. We report a rare case of pyogenic liver abscess as the first manifestation of an infiltrative and penetrating hepatic flexure colon carcinoma without liver metastases. A 50-year-old woman was admitted with right abdominal pain, fever and chills.

Large size, villous content and distal location are associated with severe dysplasia in colorectal adenomas.

Unlabelled: Adenomatous polyps are precursor lesions for colorectal carcinoma. The risk of cancer development has been associated with age and size, amount of villous component and high-grade dysplasia of adenomas. The subject-related and adenoma-related risk factors for severely dysplastic lesions were further investigated.

Gastric cancer precursor lesions and Helicobacter pylori infection in patients with partial gastrectomy for peptic ulcer.

The mucosa of the gastric stump is considered at greater risk of dysplastic and neoplastic changes than that of the intact stomach. The combination of enteric reflux and Helicobacter pylori infection may have a synergistic damaging effect on the mucosa of the gastric remnant, both producing and increasing mucosal proliferation. The aim of this study was to assess whether the occurrence of H.

Is desmoplasia a protective factor for survival in patients with colorectal carcinoma?

Background & Aims: The role of desmoplasia in colorectal carcinoma progression is unclear and the presence of collagen stroma may represent a barrier against cancer diffusion and vascular invasion or a stroma to build up and support the tumor. The aim of this study was to evaluate the effect of desmoplastic response on long-term survival of patients who underwent radical resection for colorectal carcinoma.

Methods: The study included 429 patients who underwent radical colorectal resection for cancer with a median follow-up period of 72.

A late complication of pelvic radiotherapy: leiomyosarcoma of the rectum. Report of a case and review of the literature.

Leiomyosarcoma of the rectum is an uncommon malignancy; it accounts for less than 0.1% of all malignancies of the colon and rectum and only one case has been reported long-term following pelvic radiotherapy. We report a second case of leiomyosarcoma of the rectum after radiotherapy in an elderly women who received external radiation therapy eighteen years before, for endometrial carcinoma.