Erythema nodosum leprosum necroticans: a case report of an atypical severe type 2 leprosy reaction and literature review.

Until now, leprosy remains a problem and challenge in the world because it can cause disability and morbidity in affected individuals, including problems due to the emergence of type 2 lepra reaction or erythema nodosum leprosum (ENL). The clinical picture of ENL can appear in an atypical and severe form, called ENL necroticans (ENN), which becomes a problem in diagnosis and therapy. We report a 17-year-old female with lepromatous leprosy and ENN who received therapy in the form of a combination of steroids and methotrexate.

Malignant syphilis: an early feature of underlying HIV infection in an MSM patient.

Introduction: Co-infection of human immunodeficiency virus (HIV) with syphilis is common and has significant clinical consequences. HIV infection can change the course and clinical manifestations of syphilis, resulting in atypical syphilis. A rare feature of this infection is malignant syphilis, which frequently resembles other skin lesions and poses a challenge in diagnosis.

Impact of pandemic COVID-19 on dermatology and venereology outpatient clinic in a tertiary referral hospital in Yogyakarta, Indonesia.

COVID-19 has spread throughout the world rapidly, including in Indonesia. During this pandemic, there are differences in the number and types of patient cases who attend the dermatology and venereology outpatient clinic. This study aimed to investigate the differences in the number of cases, disease profiles, diagnostic procedures, and therapy procedures before and during the COVID-19 pandemic in the dermatology and venereology outpatient clinic in Dr.