Publications by authors named "Alessandra Previdi"
Novel thermostable amine transferases from hot spring metagenomes.
Appl Microbiol Biotechnol
June 2017
Article Synopsis
- Researchers investigated hot spring metagenomes from Iceland and Italy to identify new amine transaminases (ATAs), which are enzymes useful for creating optically pure amines.
- Three novel (S)-selective ATAs—Is3-TA, It6-TA, and B3-TA—were successfully cloned, with B3-TA proving to be the most thermostable, maintaining significant activity even after prolonged exposure to high temperatures.
- These findings suggest that B3-TA and the newly discovered ATAs have potential practical applications in biocatalysis due to their ability to perform efficiently under extreme conditions and in various solvents.