Fluoroquinolones or fortified antibiotics for treating bacterial keratitis: systematic review and meta-analysis of comparative studies.

Objective: To review published clinical studies having compared fluoroquinolones with fortified antibiotics in the treatment of bacterial keratitis.

Design: Systematic review of randomized and nonrandomized trials published between 1991 and 2011, and meta-analysis of efficacy results.

Participants: Eight randomized and 5 nonrandomized studies comparing the efficacy and safety of fortified antibiotics or fluoroquinolones for treating bacterial keratitis.

[Fraser syndrome: case report].

Fraser syndrome is a systemic condition characterized by cryptophthalmos, syndactyly and abnormal genitalia, which may be associated with urinary tract, ear, nose, larynx and skeletal abnormalities. Cryptophthalmos can be an isolated finding (that has been reported as an autosomal dominant trait) or associated with other congenital anomalies (reported as an autosomal recessive disorder). RMSA, female, 3 m.

[Ocular changes induced by chemotherapy].

Antineoplastic agents offer an increase in the patients' survival rates, but may induce side effects in different organs and tissues. Mucositis is one of the most common side effects during chemotherapy with certain agents. The ocular toxicity induced by these drugs may manifest as changes in the ocular surface and in the tear film.