Publications by authors named "Alessandra Orlandini"
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Synopsis of recent research by authors named "Alessandra Orlandini"
- Alessandra Orlandini's recent research focuses primarily on the clinical aspects and treatment outcomes of Hepatitis C Virus (HCV) infections, particularly emphasizing T cell exhaustion and the effectiveness of antiviral therapies across different patient demographics.
- Key findings include the identification of mechanisms behind CD8+ T cell exhaustion during HCV infection and the potential for histone methyltransferase inhibitors to restore T cell functionality, alongside demonstrating high sustained virological response (SVR) rates with various direct-acting antiviral treatments in cirrhotic patients.
- Overall, her work highlights the importance of effective treatment regimens and patient management strategies to facilitate HCV elimination goals set by global health organizations, supported by real-world data and innovative modeling approaches.
