Publications by authors named "Alessandra Maria Montalverne Pierre"
Effectiveness and Safety of Direct-Acting Antivirals in the Treatment of Chronic Hepatitis C: A Real-life Study in Northeastern Brazil.
Elodie Bomfim Hyppolito Alberto Novaes Ramos Larissa Peixoto Teixeira Arthur Machado Bezerra Lucas Arruda Mendes Alessandra Maria Montalverne Pierre
Rev Soc Bras Med Trop
November 2024
Article Synopsis
- The study evaluated the effectiveness and safety of direct-acting antivirals (DAAs) for hepatitis C, focusing on sustained virologic response (SVR) and serious adverse events among patients in Ceará, Brazil.
- A total of 1075 patients were analyzed, with a high overall SVR rate of 96.4%; however, those with cirrhosis showed slightly lower SVR rates compared to patients with less severe fibrosis.
- While DAAs were generally safe, a small percentage (3.5%) of patients experienced serious adverse events, and some decompensated cirrhosis patients faced mortality during treatment.
Context: Retinal vein thrombosis is most common in old people, and is often associated with systemic vascular disease. One of its rare systemic causes is protein S deficiency.
Case Report: A case of a 21-year-old woman with retinal vein prethrombosis associated only with protein S deficiency is described.