Publications by authors named "Alessandra Maria Bavo"

Background: Device-related thrombosis (DRT) occurs in up to 4% of patients undergoing left atrial appendage occlusion (LAAO) and is associated with substantial morbidity and mortality. However, its pathophysiology, predictors, and optimal management remain unclear.

Objectives: This study aims to assess flow dynamic factors correlating to DRT.

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Article Synopsis
  • The study investigates the impact of excluding the left atrial appendage (LAA) on blood flow dynamics in patients with atrial fibrillation, who are at risk of stroke and bleeding.
  • Computational fluid dynamics simulations were performed for nine patients, analyzing various flow parameters before and after LAA exclusion.
  • Results indicated a significant decrease in Time Averaged Wall Shear Stress and low-magnitude velocities, alongside slight increases in Oscillatory Shear Index, Relative Residence Time, and pressure; further research is needed to understand the clinical significance of these changes.
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Background: The number of multislice computed tomography (MSCT) analyses performed for planning structural heart interventions is rapidly increasing. Further automation is required to save time, increase standardization, and reduce the learning curve.

Objective: The purpose of this study was to investigate the feasibility of a fully automated artificial intelligence (AI)-based MSCT analysis for planning structural heart interventions, focusing on left atrial appendage occlusion (LAAO) as the selected use case.

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