Experience with cinacalcet in primary hyperparathyroidism: results after 1 year of treatment.

Objectives: To assess the characteristics of patients with primary hyperparathyroidism (PHPT) treated with cinacalcet and to evaluate its efficacy in reducing serum calcium and parathyroid hormone (PTH) concentrations after 1 year of treatment.

Methods: The study included 20 patients with PHPT who had completed at least 12 months of treatment with cinacalcet (eight patients for refusal of parathyroidectomy, three for surgery not possible due to comorbidities and nine for progressive hypercalcemia prior to surgery). We recorded clinical and biochemical data at baseline, and after 3, 6 and 12 months of treatment.

Metabolic and cardiovascular risk factor control in a diabetic cohort. Four-year results.

Objectives: To assess control of blood glucose and other cardiovascular risk factors in diabetic patients monitored at an outpatient endocrinology clinic. To ascertain treatment used and its changes over time.

Patients And Methods: A cohort of 424 randomly selected diabetic patients (both type 1 and type 2) was monitored from 2004 to 2008.