Publications by authors named "Alessandra E Thomann"

Background: Early and accurate detection of cognitive changes using simple tools is essential for an appropriate referral to a more detailed neurocognitive assessment and for the implementation of therapeutic strategies. The Mini-Mental Status Examination (MMSE) and the Montreal Cognitive Assessment (MoCA) are two commonly used psychometric tests for cognitive screening. Both tests have different strengths and weaknesses.

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Background: Evaluating the discrepancies between patient-reported measures and clinician examination has implications for formulating individual treatment regimens.

Objective: This study investigated the association between health outcomes and level of self-reported motor-related function impairment relative to clinician-examined motor signs.

Methods: Recently diagnosed PD patients were evaluated using the Parkinson's Progression Marker Initiative (PPMI, N = 420) and the PASADENA phase II clinical trial (N = 316).

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Article Synopsis
  • The study evaluates the Montreal Cognitive Assessment (MoCA) and aims to improve its cut-off score for diagnosing cognitive impairment, as the original score of 25/26 lacks specificity.
  • Researchers analyzed data from nearly 800 participants, finding that a new cut-off score of 23/24 improved classification rates and specificity significantly compared to the original.
  • Introducing two distinct cut-offs enhances diagnostic accuracy, allowing more precise cognitive screenings, especially for individuals with scores in the undecided range.
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Background: The Montreal Cognitive Assessment (MoCA) is used to evaluate multiple cognitive domains in elderly individuals. However, it is influenced by demographic characteristics that have yet to be adequately considered.

Objective: The aim of our study was to investigate the effects of age, education, and sex on the MoCA total score and to provide demographically adjusted normative values for a German-speaking population.

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Background: Preexisting cognitive impairment in surgical patients is one of the leading risk factors for adverse cognitive outcomes such as postoperative delirium and postoperative cognitive dysfunction. We developed a self-administered tablet computer application intended to assess the individual risk for adverse postoperative cognitive outcomes. This cross-sectional study aimed to establish normative data for the tool.

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