Publications by authors named "Alessandra Di Giovanni"

Objective: To report our 3-year institutional experience of total laparoscopic (TL) segmental sigmoid colon/rectal resection for treatment of bowel endometriosis (BE).

Design: The TrEnd trial is a single-institutional retrospective/prospective study conducted with the aim of systematically collecting data from consecutive patients undergoing segmental colorectal resection for BE. This paper reports the outcomes of patients undergoing intracorporeal anastomosis and transanal natural orifice specimen extraction (NOSE) from this database.

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Objective: To show the surgical steps used to perform a laparoscopic double discoid colorectal resection for the excision of 2 distinct deep endometriotic nodules (DENs).

Design: Stepwise demonstration of the technique with narrated video footage.

Setting: To date there is agreement that discoid resection should be the first choice procedure in patients eligible for surgical treatment with rectal, unifocal DENs measuring ≤ 3 cm [1-3].

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Study Objective: To investigate the postoperative morbidity of laparoscopic hysterectomy (LH) for endometriosis/adenomyosis in terms of operative outcomes and complications.

Design: Retrospective multicentric cohort study.

Setting: Eight European minimally invasive referral centers.

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The objective of this work is to assess the 5-year outcomes of patients undergoing conization for high-grade cervical lesions that simultaneously present as risk factors in the persistence of HPV infection and the positivity of surgical resection margins. This is a retrospective study evaluating patients undergoing conization for high-grade cervical lesions. All patients included had both positive surgical margins and experienced HPV persistence at 6 months.

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Objective: To calculate the predictive value and thus the clinical usefulness of transvaginal ultrasound (US) imaging for the management of deep endometriosis, knowing that the positive predictive value (PPV) varies with the prevalence and probably with the volume and location of the disease.

Data Sources: After registration on PROSPERO (CRD42022366323), PubMed was searched for all reports describing the diagnostic accuracy of US imaging for deep endometriosis published between January 1, 2000, and October 20, 2022.

Methods Of Study Selection: The 536 articles on "endometriosis AND US And diagnosis" were hand searched, and 30 reports describing sensitivity and specificity of deep endometriosis were found.

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Study Objective: To compare the accuracy of preoperative ultrasound (US) in predicting the laparoscopically defined 2021 American Association of Gynecologic Laparoscopists (AAGL) Endometriosis Staging.

Design: Retrospective multicenter study of patients treated at 3 specialized endometriosis centers.

Setting: Three specialized endometriosis surgical centers in São Paulo (Brazil), Barcelona (Spain), and Avellino (Italy) participated.

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Article Synopsis
  • The study compares the #Enzian classification and the revised American Society for Reproductive Medicine (rASRM) stages in assessing the extent of endometriosis in women undergoing radical surgery for deep endometriosis.
  • Findings show that while the severity of endometriotic lesions and adhesions generally increases with higher rASRM stages, deep endometriosis can also occur in early stages, leading to potential underestimation of disease severity.
  • The research involved 735 women and indicates that many with rASRM stage 1 had significant deep endometriosis, highlighting the need for better classification methods.
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Study Objectives: To assess the value of combined transvaginal/transabdominal ultrasonographic evaluation performed by experienced examiners for deep infiltrating endometriosis (DIE) lesions of the retrocervical (torus uterinus and uterosacral ligaments) and parametrial areas and summarize the features and anatomic criteria for identification of these lesions and their extent in the above-mentioned pelvic compartments.

Design: Retrospective study.

Setting: A specialized endometriosis center in Avellino, Italy.

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Purpose: To compare the location and sizes of deep endometriosis (DE) lesions evaluated by preoperative transvaginal sonography (TVS) in different #Enzian compartments with intraoperatively assessed DE location and size.

Materials And Methods: Retrospective data analysis of 93 women undergoing TVS and surgery for DE in 2019 at a tertiary referral center for endometriosis.

Results: #Enzian compartment C (rectum) showed the highest rate of exact concordance with 74% of cases, which increased to 87% when a tolerance margin of a maximum of 3mm for TVS measurements was taken into account.

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Objective: To show the surgical steps used to perform a totally laparoscopic segmental rectal resection, with intracorporeal anastomosis and transanal natural orifice specimen extraction (NOSE), in a context of deep endometriosis.

Design: Step-by-step video demonstration of the technique.

Setting: Even though the combined use of intracorporeal anastomosis and NOSE has increasingly been investigated during the last decade, there is still lack of defined consensus, both in terms of patient eligibility and operative technique.

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Objective: To show the surgical steps used to perform a rectal disc excision in the context of deep infiltrating endometriosis characterized by contiguity between an intestinal lesion and the retrocervical region.

Design: Step-by-step video demonstration of the technique.

Setting: Although surgical options for the management of rectosigmoid endometriosis have been investigated increasingly, there is no consensus regarding patient eligibility for shaving, discoid resection, or segmental resection.

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Study Objective: To identify bowel nodule features of deep infiltrating endometriosis (DIE) measured through preoperative ultrasound scanning that influence laparoscopic surgical strategy.

Design: A retrospective study.

Setting: Malzoni Clinic-Endoscopica Malzoni Department, Center for Advanced Endoscopic Gynecological Surgery, Avellino, Italy.

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Study Objective: To demonstrate the surgical steps involved in segmental rectosigmoid resection and reanastomosis in a deep infiltrating endometriosis (DIE) setting.

Design: Step-by-step video demonstration of the technique.

Setting: Despite efforts made to identify criteria able to reliably predict which patients would be more likely to benefit from segmental bowel resection, such predictability remains an area of controversy and ambiguity.

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Study Objective: To assess the sensitivity and accuracy of combined transvaginal/ transabdominal ultrasonography (TV/TA US) for evaluation of deep infiltrating bowel endometriosis nodules measured after surgery.

Design: Prospective study (Canadian Task Force classification II.1).

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Study Objective: To evaluate the feasibility and safety of laparoscopic segmental bowel resection for deep infiltrating endometriosis (DIE).

Design: Retrospective clinical study (Canadian Task Force classification II-3).

Setting: Endoscopica Malzoni-Center for Advanced Endoscopic Gynecological Surgery, Avellino, Italy.

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Objective: To assess the accuracy of transvaginal sonography (TVS) in defining size and location of deep infiltrating endometriosis (DIE) with laparoscopic/histologic confirmation.

Design: Prospective observational study.

Setting: University hospital.

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Objectives: Deep infiltrating endometriosis (DIE) represents the most complex form of endometriosis and its treatment is still challenging. The coexistence of DIE with other appearances of endometriosis stimulates new studies to improve the preoperative diagnosis. Adenomyosis is a clinical form that shares several symptoms with DIE.

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Study Objective: To determine whether transvaginal hysterosalpingo-contrast sonography (HyCoSy) with a new dedicated contrast-enhanced ultrasound technique, can contribute to accurate diagnosis of tubal occlusion.

Design: Prospective observational study (Canadian Task Force classification II-2).

Setting: University hospital.

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Objective: To report a case of bilateral ovarian pregnancy in a young patient who had previously undergone intrauterine insemination (IUI) and controlled ovarian stimulation (COS).

Design: Case report.

Setting: University hospital.

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Study Objective: Classic myomectomy was performed via laparotomy. More recently, laparoscopic myomectomy has become a valuable treatment option. Vaginal myomectomy is a surgical procedure that has recently been evaluated.

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