Clinical significance of eosinophilia and chronic inflammatory infiltrate in children's rectal biopsies.

Aims: The aim of the present study was to determine the clinical significance of an incidental finding of eosinophilia (EOS) and chronic inflammatory infiltrate (CINF) in rectal biopsies of children investigated for suspected Hirschsprung disease (HSCR).

Methods: A retrospective study (2000-2010) of children incidentally found to have EOS and CINF was performed. HSCR cases were excluded.