Publications by authors named "Alessandra Braus"

Objectives: The UK Prospective Diabetes Study (UKPDS) Risk Engine (RE) provides the best risk estimates available for people with type 2 diabetes (T2D), so it was applied to patients on persistent sitagliptin treatment.

Design: A 'real-world' retrospective, observational, single-center study.

Setting: The study was performed in a general hospital in Northern Italy in order: (1) to validate UKPDS RE in a cohort of Italian participants with T2D without prespecified diabetes duration, with/without cardiovascular (CV) disease, treated with sitagliptin; (2) to confirm CV risk gender difference; (3) to evaluate the effect on metabolic control and on CV risk evolution obtained by 'add-on' persistent sitagliptin treatment.

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Background: A paucity of data exists to examine nurses' satisfaction with the use of insulin pens with safety needles in hospitalized patients with diabetes. We investigated major determinants of nurses' preference of the method of insulin administration in the context of a General Hospital in Northern Italy.

Methods: Consecutive patients admitted to three hospital units of different care intensity requiring insulin received insulin therapy through either the vial/syringe method (October to December 2012) or pen/safety needles with dual-ended protection method (January to March 2013).

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Article Synopsis
  • - The study evaluated the costs and safety of insulin pen devices versus traditional syringes in hospitalized patients requiring insulin therapy over a 9-month period in Northern Italy.
  • - 360 patients were analyzed, revealing that while insulin pens had a higher direct cost, they offered estimated savings when factoring in indirect costs and needlestick injuries, leading to a net savings of 32 euros per patient.
  • - Patient safety was consistent across methods, but significantly more patients expressed a preference for continuing insulin therapy with pens at home compared to syringes (74% vs. 12%).
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