Publications by authors named "Alessandra Bosutti"
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Synopsis of recent research by authors named "Alessandra Bosutti"
- Alessandra Bosutti's research primarily focuses on the effects of bed rest and disuse on skeletal muscle metabolism and physiology, exploring mechanisms such as insulin sensitivity, muscle atrophy, and oxidative capacity during periods of inactivity.
- Her studies utilize a variety of methodologies, including integrative approaches for assessing muscle metabolism, pharmacological activation of ion channels, and transgenic models, to elucidate key physiological adaptations and potential countermeasures to muscle degradation.
- Findings from her work indicate significant metabolic changes in skeletal muscle during bed rest, including a decrease in insulin sensitivity and alterations in glycogen metabolism, as well as the impact of Piezo1 channels on muscle regeneration and function, suggesting avenues for therapeutic intervention in muscle-wasting conditions.