Publications by authors named "Alessandra Bitti"
Article Synopsis
- A new prognostic model for COVID-19 progression was developed to include vaccination status and early treatment, which were missing from previous scores.
- The study analyzed data from 1,145 patients in Sassari, revealing that older age, comorbidities, and lack of vaccination were linked to disease progression, where 29.3% of patients required supplemental oxygen.
- Multivariate analysis identified key risk factors for progression and created an easy-to-use scoring system based on various clinical and demographic variables, enhancing the ability to predict patient outcomes.
Since the start of the SARS-CoV-2 pandemic, several treatments have been proposed to prevent the progression of the disease. Currently, three antiviral (molnupiravir, nirmaltrevir/r, remdesivir) and two monoclonal antibodies (casirivimab/imdevimab and sotrovimab) are available in Italy. Therefore, we aimed to evaluate the presence of risk factors associated with disease progression.
View Article and Find Full Text PDFSince the start of the SARS-CoV-2 pandemic, several scores have been proposed to identify infected individuals at a higher risk of progression and death. The most famous is the 4C score. However, it was developed in early 2020.
View Article and Find Full Text PDFSince the start of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic, several treatments have been proposed to cure coronavirus disease 2019 (COVID-19) and prevent it. Molnupiravir is a ribonucleoside prodrug of N-hydroxycytidine with an in vitro and in vivo activity against SARS-CoV-2. We conducted a retrospective cohort study that included all people treated with molnupiravir between January 10, 2022, and March 31, 2022, at the University Hospital of Sassari.
View Article and Find Full Text PDF