Publications by authors named "Alessandra Binco"
Article Synopsis
- The study looked at patients with pancreatic cancer who were supposed to have surgery to remove their tumors and focused on how often those surgeries were completed.
- Out of 681 patients, most were able to have their surgeries, but some couldn’t because the cancer spread more than expected or was too difficult to remove.
- Patients who did have surgery lived longer (around 30-36 months) compared to those who couldn’t have the surgery, who lived about a year.
Objective: The aim of this study was to develop and validate a pretreatment prognostic score in pancreatic cancer (PDAC).
Background: Pretreatment prognostication in PDAC is important for treatment decisions but remains challenging. Available prognostic tools are derived from selected cohorts of patients who underwent resection, excluding up to 20% of patients with exploration only, and do not adequately reflect the pretreatment scenario.
Importance: Chemotherapy is the recommended induction strategy in borderline resectable and locally advanced pancreatic ductal adenocarcinoma. However, the associated results on an intention-to-treat basis are poorly understood.
Objective: To investigate pragmatically the treatment compliance, conversion to surgery, and survival outcomes of patients with borderline resectable and locally advanced pancreatic ductal adenocarcinoma undergoing primary chemotherapy.