Improved creatinine-based early detection of acute kidney injury after cardiac surgery.

Objectives: This study aims to improve early detection of cardiac surgery-associated acute kidney injury (CSA-AKI) compared to classical clinical scores.

Methods: Data from 7633 patients who underwent cardiac surgery between 2008 and 2018 in our institution were analysed. CSA-AKI was defined according to the Kidney Disease Improving Global Outcomes (KDIGO) criteria.

C3 glomerulopathy in children: Is there still a place for anti-cellular immunosuppression?

Aim: To contribute additional clinical experience to the paucity of reports on C3 glomerulopathy (C3GP) in children, we are reporting our cohort of 11 children with C3GP, emphasizing the therapeutic options in this peculiar entity.

Methods: We describe the incidence, manifestation, histopathology findings, follow-up, treatment and outcome of C3GP in 11 children with C3GP by retrospectively analyzing their clinical charts and renal biopsy reports.

Results: Eleven C3GP patients were identified among 240 children who had undergone renal biopsy, accounting for a 4.