Background: The need for scientific knowledge about aging is predicated on the demand of modern society to extend the active life of a person. To maintain intellectual longevity, it is necessary to take into account not only the pathological, but also compensatory mechanisms that arise during aging. The cerebral-cognitive reserve (CCR) influences the rate of transition from pre-phenomenological stages to the clinical stage of the disease, thereby changing the prognosis of Alzheimer's disease (AD).
View Article and Find Full Text PDFAutism spectrum disorder (ASD) includes a heterogeneous group of complex neurodevelopmental disorders characterized by atypical behaviors with two core pathological manifestations: deficits in social interaction/communication and repetitive behaviors, which are associated with disturbed redox homeostasis. Modulation of cellular resilience mechanisms induced by low levels of stressors represents a novel approach for the development of therapeutic strategies, and in this context, neuroprotective effects of a wide range of polyphenol compounds have been demonstrated in several in vitro and in vivo studies and thoroughly reviewed. Mushrooms have been used in traditional medicine for many years and have been associated with a long list of therapeutic properties, including antitumor, immunomodulatory, antioxidant, antiviral, antibacterial, and hepatoprotective effects.
View Article and Find Full Text PDFPreservation of health, increase in life expectancy determine the need to improve the effectiveness of medical recommendations, which, despite the success of pharmacology, are insufficient for reasons related to the low level of compliance with these recommendations by patients. The authors of the article believe that compliance is a kind of quantifiable and behaviorally realized reflection of therapeutic interaction, refracted through the prism of the patient's individual personality characteristics. Participants of the study-148 employees of medical institutions: 12 men, 136 women, their age ranged from 27 to 74 years.
View Article and Find Full Text PDFBackground: The high risk of cognitive impairment in people of older age groups determines the relevance of the study of factors contributing to the preservation of cognitive potential at a young age, which is necessary to develop a cognitive reserve model aimed at preventing the transformation of physiological aging into pathological. Purpose, to identify the importance of the "gender" factor for the formation of a cognitive reserve.
Materials And Methods: The research material was scientific publications on the topic of work.