Publications by authors named "Alena Grabowski"

Elite distance runners have exhibited race time improvements since the 2020 introduction of advanced footwear technology (AFT) for track and field, also known as "super" spikes. The observed performance improvements may be due to changes in midsole compliance, which could affect leg stiffness while wearing AFT spikes. Since increased leg stiffness has been associated with running speeds greater than 6 m/s, race time improvements for elite distance runners wearing AFT spikes may be reduced at faster running speeds.

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People with unilateral transtibial amputation (TTA) using a passive-elastic prosthesis exhibit lower positive affected leg trailing work (AL W) and a greater magnitude of negative unaffected leg leading work (UL W) during walking than non-amputees, which may increase joint pain and osteoarthritis risk in the unaffected leg. People with TTA using a stance-phase powered prosthesis (e.g.

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Similar to nonamputees, female athletes with unilateral transtibial amputation (TTA) using running-specific leg prostheses (RSPs) may have worse running economy and higher rates of running-related injury than male athletes. Optimizing RSP configuration for female athletes could improve running economy and minimize biomechanical asymmetry, which has been associated with running-related injury. Nine females with a TTA ran at 2.

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Purpose: We determined the effects of shorter affected side (AS) crank arm lengths and cycling with two different prostheses on joint and crank power, asymmetry, and net efficiency.

Methods: Twelve participants with a TTA rode at 1.5 W·kg -1 with equal (175 mm) and shorter AS crank arms (160, 165, 170 mm) using a daily-use prosthesis and CSP.

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Humans change joint quasi-stiffness ( ) and leg stiffness (k) when running at different speeds on level ground and during uphill and downhill running. These mechanical properties can inform device designs for running such as footwear, exoskeletons and prostheses. We measured kinetics and kinematics from 17 runners (10 M; 7 F) at three speeds on 0°, ±2°, ±4° and ±6° slopes.

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Passive, full-leg exoskeletons that act in parallel with the legs can reduce the metabolic power of bouncing gaits like hopping. However, the magnitude of metabolic power reduction depends on the spring stiffness profile of the exoskeleton and is presumably affected by how users adapt their lower-limb joint mechanics. We determined the effects of using a passive, full-leg exoskeleton with degressive (DG), linear (LN) and progressive (PG) stiffness springs on lower-limb joint kinematics and kinetics during stationary, bilateral hopping at 2.

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Introduction: Passive-elastic prosthetic feet are manufactured with numerical stiffness categories and prescribed based on the user's body mass and activity level, but mechanical properties, such as stiffness values and hysteresis are not typically reported. Since the mechanical properties of passive-elastic prosthetic feet and footwear can affect walking biomechanics of people with transtibial or transfemoral amputation, characterizing these properties can provide objective metrics for comparison and aid prosthetic foot prescription and design.

Methods: We characterized axial and torsional stiffness values, and hysteresis of 33 categories and sizes of a commercially available passive-elastic prosthetic foot model [Össur low-profile (LP) Vari-flex] with and without a shoe.

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Humans attain slower maximum velocity (vmax) on curves versus straight paths, potentially due to centripetal ground reaction force (GRF) production, and this depends on curve radius. Previous studies found GRF production differences between an athlete's inside versus outside leg relative to the center of the curve. Further, sprinting clockwise (CW) versus counterclockwise (CCW) slows vmax.

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We aimed to determine a method for prescribing a standing prosthetic leg length (ProsL) that results in an equivalent running biological leg length (BioL) for athletes with unilateral (UTTA) and bilateral transtibial amputations (BTTA). We measured standing leg length of ten non-amputee (NA) athletes, ten athletes with UTTA, and five athletes with BTTA. All athletes performed treadmill running trials from 3 m/s to their maximum speed.

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People with transtibial amputation (TTA) using passive-elastic prostheses have greater leg muscle activity and metabolic cost during level-ground and sloped walking than non-amputees. Use of a stance-phase powered (BiOM) versus passive-elastic prosthesis reduces metabolic cost for people with TTA during level-ground, +3° and +6° walking. Metabolic cost is associated with muscle activity, which may provide insight into differences between prostheses.

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People with lower limb impairment can participate in activities such as running with the use of a passive-dynamic ankle-foot orthosis (PD-AFO). Specifically, the Intrepid Dynamic Exoskeletal Orthosis (IDEO) is a PD-AFO design that includes a carbon-fiber strut, which attaches posteriorly to a custom-fabricated tibial cuff and foot plate and acts in parallel with the impaired biological ankle joint to control sagittal and mediolateral motion, while allowing elastic energy storage and return during the stance phase of running. The strut stiffness affects the extent to which the orthosis keeps the impaired biological ankle in a neutral position by controling sagittal and mediolateral motion.

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The volume of active muscle and duration of extensor muscle force well explain the associated metabolic energy expenditure across body mass and velocity during level-ground running and hopping. However, if these parameters fundamentally drive metabolic energy expenditure, then they should pertain to multiple modes of locomotion and provide a simple framework for relating biomechanics to metabolic energy expenditure in bouncing gaits. Therefore, we evaluated the ability of the 'cost of generating force' hypothesis to link biomechanics and metabolic energy expenditure during human running and hopping across step frequencies.

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Athletes with transtibial amputation (TTA) use running-specific prostheses (RSPs) to run. RSP configuration likely affects the biomechanics of such athletes across speeds. We determined how the use of three RSP models (Catapult, Sprinter and Xtend) with three stiffness categories (recommended, ±1), and three heights (recommended, ±2 cm) affected contact length ( ), stance average vertical ground reaction force ( ), step frequency ( ) and asymmetry between legs for 10 athletes with unilateral TTA at 3-7 m s.

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Running-prostheses have enabled exceptional athletes with bilateral leg amputations to surpass Olympic 400 m athletics qualifying standards. Due to the world-class performances and relatively fast race finishes of these athletes, many people assume that running-prostheses provide users an unfair advantage over biologically legged competitors during long sprint races. These assumptions have led athletics governing bodies to prohibit the use of running-prostheses in sanctioned non-amputee (NA) competitions, such as at the Olympics.

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Background: Ground reaction forces (GRFs) are important for understanding human movement, but their measurement is generally limited to a laboratory environment. Previous studies have used neural networks to predict GRF waveforms during running from wearable device data, but these predictions are limited to the stance phase of level-ground running. A method of predicting the normal (perpendicular to running surface) GRF waveform using wearable devices across a range of running speeds and slopes could allow researchers and clinicians to predict kinetic and kinematic variables outside the laboratory environment.

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Background: Stress fractures are injuries caused by repetitive loading during activities such as running. The application of advanced analytical methods such as machine learning to data from multiple wearable sensors has allowed for predictions of biomechanical variables associated with running-related injuries like stress fractures. However, it is unclear if data from a single wearable sensor can accurately estimate variables that characterize external loading during running such as peak vertical ground reaction force (vGRF), vertical impulse, and ground contact time.

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Inertial measurement units (IMUs) are popular tools for estimating biomechanical variables such as peak vertical ground reaction force (GRF) and foot-ground contact time (t), often by using multiple sensors or predictive models. Despite their growing use, little is known about the effects of varying low-pass filter cutoff frequency, which can affect the magnitude of force-related dependent variables, the accuracy of IMU-derived metrics, or if simpler methods for such estimations exist. The purpose of this study was to investigate the effects of varying low-pass filter cutoff frequency on the correlation of IMU-derived peak GRF and t to gold-standard lab-based measurements.

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In Duchenne muscular dystrophy (DMD), one of the most severe and frequent genetic diseases in humans, dystrophic muscles are prone to damage caused by mechanical stresses during eccentric contractions. Eccentric contraction during walking on level ground likely contributes to the progression of degeneration in lower limb muscles. However, little is known about how the amount of muscle eccentric contractions is affected by uphill/downhill sloped walking, which is often encountered in patients' daily lives and poses different biomechanical demands than level walking.

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Background: Previous studies have shown that passive-elastic exoskeletons with springs in parallel with the ankle can reduce the metabolic cost of walking. We developed and tested the use of an unpowered passive-elastic exoskeleton for walking that stores elastic energy in a spring from knee extension at the end of the leg swing phase, and then releases this energy to assist ankle plantarflexion at the end of the stance phase prior to toe-off. The exoskeleton uses a system of ratchets and pawls to store and return elastic energy through compression and release of metal springs that act in parallel with the knee and ankle, respectively.

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Purpose: we determined the metabolic and biomechanical effects of adding mass to the running-specific prosthesis (RSP) and biological foot of individuals with a unilateral transtibial amputation (TTA) during running.

Methods: 10 individuals (8 males, 2 females) with a TTA ran on a force-measuring treadmill at 2.5 m/s with 100 g and 300 g added to their RSP alone or to their RSP and biological foot while we measured their metabolic rates and calculated peak vertical ground reaction force (vGRF), stance-average vGRF, and step time symmetry indices.

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Running-specific prostheses (RSPs) have facilitated an athlete with bilateral transtibial amputations to compete in the Olympic Games. However, the performance effects of using RSPs compared to biological legs remains controversial. Further, the use of different prosthetic configurations such as shape, stiffness, and height likely influence performance.

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The metabolic cost of walking is due to muscle force generated to support body weight (BW), external work performed to redirect and accelerate the center of mass (CoM), and internal work performed to swing the limbs and maintain balance. We hypothesized that BW support would incur a greater and lower percentage of Net Metabolic Power (NMP) for uphill and downhill slopes, respectively, compared to level-ground walking. Additionally, we hypothesized that mass redirection would incur a greater and lower percentage of NMP for uphill and downhill slopes, respectively compared to level-ground walking.

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