Publications by authors named "Alen James"
Article Synopsis
- Biomolecules in living cells experience crowded environments due to high concentrations of cosolutes and macromolecules, affecting their dynamics and structure.
- This study uses molecular dynamics simulations to analyze how confinement and the presence of cosolutes like urea influence the collapse equilibria of three different model polymers.
- The findings reveal that confinement usually promotes polymer collapse, but the effects of urea vary: it weakens collapses in hydrophobic polymers while enhancing collapses in hydrophilic ones, leading to complex interactions that impact the stability of biomolecules in cells.
