Publications by authors named "Alemwosen Alem"

Background: To address the need for a skilled workforce in breast cancer (BC) pathology in sub-Saharan Africa (SSA), we implemented an education program to train laboratory technicians in manual immunohistochemistry (IHC).

Methods: A quality improvement education project was developed. Interactive webinars were held every six months with didactics and presentations from African experts with experience in IHC.

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Article Synopsis
  • The study examines breast cancer (BC) subtypes across four Ethiopian regions, highlighting a lack of research in areas outside Addis Ababa.
  • Researchers analyzed 227 tissue samples using immunohistochemistry to determine the presence of key markers and found high rates of ER and PR negativity, as well as a significant prevalence of triple-negative breast cancer (TNBC) at 33.1%.
  • The findings indicate that a substantial proportion of patients may not benefit from standard endocrine treatments, and the high occurrence of aggressive tumors in younger patients suggests a need for tailored treatment approaches.
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Breast cancer (BC) is the most common type of cancer in Ethiopia. The incidence of BC is also rising, but the exact figure is still poorly known. Therefore, this study was conducted to address the gap in epidemiological data on BC in southern and southwestern Ethiopia.

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Tuberculosis (TB) is a chronic granulomatous inflammatory disease that affects any part of our body. TB is a significant problem in developing countries. Intestinal TB accounts for 2% of TB cases worldwide.

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Mesenteric cysts are one of the rare causes of intra-abdominal masses. They account for 1 in 100,000 cases in adults and 1 in 20,000 cases in children. Mesenteric cysts are commonly found in the small intestine, up to 60% of cases, and occasionally in the colon.

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