Local Heating Test for Detection of Microcirculation Abnormalities in Patients with Diabetes-Related Foot Complications.

Objective: In this study, authors used a wavelet analysis of skin temperature (WAST) to assess the mechanisms of microvascular tone regulation during the local heating test in patients with diabetic foot syndrome (DFS).

Participants: The participants included control subjects and 36 hospitalized patients with DFS between 52 and 79 years old (68 ± 8 years old). They were distributed among 5 groups: 15 control subjects, 8 patients with DFS who did not develop ulcerative or necrotic disorders, 10 patients who developed the neuroischemic form of DFS complicated by foot ulceration, 12 patients with DFS complicated by toe necrosis, and 6 patients with DFS and foot gangrene.

Detection of Endothelial Dysfunction Using Skin Temperature Oscillations Analysis During Local Heating in Patients With Peripheral Arterial Disease.

Objective: The purpose of this study was to examine correlations between laboratory markers of ED and the degree of endothelium-dependent vasodilation using WAST during a local heating test in patients with PAD.

Materials And Methods: The study population consisted of 17 healthy subjects and 38 patients with PAD. The ST on the plantar surface of the first toe was measured during the test, and the inverse wavelet transform was applied to reconstruct the ST signals in three frequency bands corresponding to myogenic, neurogenic, and endothelial mechanisms of vascular tone regulation.