An in vitro and in vivo study on the intensity of adhesion and colonization by Staphylococcus epidermidis and Pseudomonas aeruginosa on originally synthesized biomaterials with different chemical composition and modified surfaces and their effect on expression of TNF-α, β-defensin 2 and IL-10 in tissues.

Unlabelled: The aim of this study was to determine adhesion and colonization of bacteria on the surface of originally synthesized glass-ceramic biomaterials and their effect on inflammation reactions in tissues surrounding the implant.

Materials And Methods: Biomaterial discs were contaminated with bacterial suspensions of 10, 10(2), and 10(3) colony forming units (CFU)/mL (P. aeruginosa ATCC 27853 and S.