Publications by authors named "Aleksei A Romanov"
Article Synopsis
- Wilson disease (WD) is caused by mutations in the ATP7B gene, leading to copper overload in the liver and brain, which can result in severe health issues.
- A mutant strain of Caenorhabditis elegans was created to study this condition, showing significant Cu sensitivity, stunted development, and other health impairments due to a specific ATP7B variant.
- The cua-1 mutant strain serves as a valuable experimental model for understanding copper toxicity in WD and testing potential therapeutic approaches.
