Publications by authors named "Aleksandra Zamaro"
Atrial Natriuretic Peptide (ANP) plays an important role in blood pressure regulation. Low levels of ANP correlate with the development of salt-sensitive hypertension (SS-HTN). Our previous studies indicated that ANP deficiency exacerbated renal function decline in SS-HTN.
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- The exocyst and a protein called Ift88 are important for making tiny structures called cilia, which help cells recover from injury.
- When Exoc5 is increased, it helps cells grow longer cilia and recover better from damage, while reducing its amount leads to problems in cells and higher levels of harmful substances.
- Mice lacking cilia showed more damage to their kidneys, highlighting how weak cilia and bad mitochondria (powerhouses of the cell) can make kidney injuries worse and disrupt a substance called tryptophan, pointing to possible new treatments.
Histamine is involved in the regulation of immune response, vasodilation, neurotransmission, and gastric acid secretion. Although elevated histamine levels and increased expression of histamine metabolizing enzymes have been reported in renal disease, there is a gap in knowledge regarding the mechanisms of histamine-related pathways in the kidney. We report here that all four histamine receptors as well as enzymes responsible for the metabolism of histamine are expressed in human and rat kidney tissues.
View Article and Find Full Text PDFBackground: Severe postoperative pain is a significant problem after cesarean sections.
Methods: This study was a randomized, controlled trial of 105 patients conducted in two hospitals. All patients were anesthetized spinally for elective cesarean section.