Publications by authors named "Aleksandra P Pitera"
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Synopsis of recent research by authors named "Aleksandra P Pitera"
- Aleksandra P Pitera's recent research primarily focuses on the integrated stress response (ISR), investigating its signaling pathways and their implications for metabolic disorders such as diabetes and neurodegenerative diseases.
- One significant finding indicates that the GCN2 activator halofuginone can enhance ISR signaling, offering protective effects against diabetes-like phenotypes in mice, thereby highlighting potential therapeutic avenues.
- Additionally, Pitera's work reveals a nuanced understanding of how various kinases and inhibitors influence the ISR, contributing to the broader knowledge of cellular responses to stress and their relevance in conditions like tauopathies.