Vertical displacements are traditionally measured with precise levelling, which is inherently time consuming. Rapid or even real-time height determination can be achieved by the Global Navigation Satellite System (GNSS). Nevertheless, the accuracy of real-time GNSS positioning is limited, and the deployment of a network of continuously operating GNSS receivers is not cost effective unless low-cost GNSS receivers are considered.
View Article and Find Full Text PDFFurin is a human serine protease responsible for activating numerous physiologically relevant cell substrates and is also involved in the development of various pathological conditions, including inflammatory diseases, cancers, and viral and bacterial infections. Therefore, compounds with the ability to inhibit furin's proteolytic action are regarded as potential therapeutics. Here we took the combinatorial chemistry approach (library consisting of 2000 peptides) to obtain new, strong, and stable peptide furin inhibitors.
View Article and Find Full Text PDFBowman-Birk inhibitors (BBIs) are found primarily in seeds of legumes and in cereal grains. These canonical inhibitors share a highly conserved nine-amino acids binding loop motif CTP1SXPPXC (where P1 is the inhibitory active site, while X stands for various amino acids). They are natural controllers of plants' endogenous proteases, but they are also inhibitors of exogenous proteases present in microbials and insects.
View Article and Find Full Text PDFBackground: Determination of quartz by Fourier transform infrared spectrometry (FTIR) is not specific: the obtained results are influenced by matrix components, some of which cause spectral interference. The aim of the study was to evaluate the effect of dust components responsible for spectral interference with quartz on the results of its determinations, and to develop methods to minimize the effects of interferences.
Material And Methods: Investigation of interferent effects were conducted using respirable dusts: quartz SRM 1878a, cristobalite SRM 1879a, synthetic amorphous silica (Zeosil) and feldspar, albite and kaolinite.
Crystalline silica is commonly found in the work environment. Possible health effects of occupational exposure continue to be the subject of extensive research. The aim of this paper was to analyze the recent findings concerning the health effects of exposure to crystalline silica, taking into account different levels of exposure.
View Article and Find Full Text PDFBackground: The aim of this study was to apply infrared spectrometry (FTIR) in mineral identification of asbestos in bulk materials.
Material And Methods: The identification of asbestos was based on infrared spectra of UICC and NIST: SRM 1866a and SRM 1867 standard asbestos, and infrared spectra of heat treatment chrysotile, crocidolite and amosite asbestos. The samples of bulk materials were grinded and fibers were isolated from samples.
Int J Occup Med Environ Health
August 2008
Crystalline silica is a health hazard commonly encountered in work environment. Occupational exposure to crystalline silica dust concerns workers employed in such industries as mineral, fuel-energy, metal, chemical and construction industry. It is estimated that over 2 million workers in the European Union are exposed to crystalline silica.
View Article and Find Full Text PDFCrystalline silica is an agent harmful to human health, and quite frequently present in occupational environments. Occupational groups exposed to crystalline silica dust include mostly workers of the mineral and coal mining as well as metallurgical, chemical and construction industries. In the European Union (EU), the number of those exposed to this agent is estimated at over 2 million persons.
View Article and Find Full Text PDFBackground: In the construction industry, free crystalline silica (FCS), mostly in the form of quartz, is in a very common use. Construction, especially repair and demolition works, are associated with emission of considerable amounts of FCS-containing dusts. Studies concerning the work environment, carried out recently in other countries, indicate that exposure to quartz frequently exceeds hygiene standards, i.
View Article and Find Full Text PDFBackground: The aim of the study was to evaluate and analyze the technical competences of workplace inspection laboratories for the determination of free crystalline silica (FCS).
Material And Methods: The study was based on the results of two series of control determinations carried out under the proficiency testing scheme in 2005 and the outcome of the questionnaire on analytical details and the quality system of laboratories. The mean values of proficiency indicies and the frequency of the obtained satisfactory performances were adopted as the basis of laboratory competences comparisons.
Background: The major objective of the study was to compare and investigate the usefulness of quantitative analyses of free crystalline silica (FCS) in the assessment of dust exposure in samples of total dust of varied composition, using three methods: chemical method in common use in Poland; infrared spectrometry; and x-ray powder diffraction.
Materials And Methods: Mineral composition and FCS contents were investigated in 9 laboratory samples of raw materials, materials, and industrial wastes, containing from about 2 to over 80% of crystalline silica and reduced to particles of size corresponding with that of total dust. Sample components were identified using XRD and FT-IR methods.