Publications by authors named "Aleksandra Lopareva"
JTO Clin Res Rep
July 2023
Article Synopsis
- Relapse after lung adenocarcinoma (LUAD) surgery is common, and this study explores how features of the tumor microenvironment (TME), specifically B-cell infiltration, impact patient survival.
- The analysis involved over 1500 LUAD specimens, using whole exome and RNA sequencing to correlate B-cell presence with relapse-free survival and overall survival (OS).
- Results indicate that a higher B-cell content is linked to better OS, especially with naive B-cells, suggesting that B-cell abundance could be an important predictor for patient outcomes following surgery.
