Publications by authors named "Aleksandra Lenart-Migdalska"
DOAC score is associated with elevated growth differentiation factor 15 and 3-nitrotyrosine in atrial fibrillation: Prediction of bleeding at one-year follow-up.
Kardiol Pol
September 2024
Neutrophil-activating peptide 2 (NAP-2, CXCL7), a platelet-derived neutrophil chemoattractant, is involved in inflammation. We investigated associations between NAP-2 levels, neutrophil extracellular traps (NETs) formation, and fibrin clot properties in atrial fibrillation (AF). We recruited 237 consecutive patients with AF (mean age, 68 ± 11 years; median CHADSVASc score of 3 [2-4]) and 30 apparently healthy controls.
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- Atrial fibrillation (AF) is linked to increased microparticle levels, indicating a hypercoagulable state, which may lead to thrombosis and thromboembolism.
- The study found that after administering rivaroxaban, both platelet-derived microparticles (PMPs) and endothelial-derived microparticles (EMPs) significantly increased in patients with nonvalvular AF.
- Statin therapy was identified as a predictor that may help reduce the release of these microparticles during rivaroxaban treatment, suggesting further investigation into their thrombotic roles is needed.
Article Synopsis
- * Results showed an increase in platelet-derived microparticles (CD42b) after dabigatran treatment, with a significant negative correlation between dabigatran concentration and changes in CD42b levels.
- * The study identified coronary artery disease (CAD) and peripheral artery disease (PAD) as independent factors influencing CD42b levels, while endothelial-derived microparticle (CD144) levels did not change after dabigatran use.
Objective: Introduction: Numerous risk factors for cardiovascular disease (CVD) are modifiable, therefore understanding their effects has a significant impact on lowering the incidence and mortality. The "Małopolska Cardiovascular Preventive Intervention Study (M-CARPI)" aims to educate the inhabitants of the voivodeship regarding preventative measures for developing CVD. The aim: To examine the effectiveness of the seminars regarding preventative measures for developing CVD according to the M-CAPRI among the inhabitants of Lesser Poland.
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- Atrial fibrillation (AF) leads to changes in the left atrium's structure and function, making it important to understand these factors to improve treatment outcomes.
- The study involved 58 patients with non-valvular AF, categorized into three groups (paroxysmal, persistent, and permanent), and assessed left atrial longitudinal strain (LALS) using advanced echocardiography techniques.
- Results showed that patients with paroxysmal AF had significantly higher LALS compared to those with persistent and permanent AF, with various independent predictors identified for LALS based on the AF type, highlighting the technique's value in assessing left atrial dysfunction.
[Evaluation of the clinical suitability of automated left ventricle's fraction and volume measurements in 3-dimensional echocardiography compared to values obtained in magnetic resonance imaging (pilot study)].
Pol Merkur Lekarski
October 2017
Unlabelled: Recently a lot of authors have been trying to determine the usefulness of 3-dimensional echocardiography (TTE 3D) in evaluation of ejection fraction and left ventricular volume, but few attempt to compare it to the current gold standard of cardiac magnetic resonance (CMR). 3D imaging technics allows to avoid errors caused by geometry of the heart chambers and foreshortened views. American Echocardiographic Guidelines recommend the use of 3-dimensional echocardiography in daily clinical practice.
View Article and Find Full Text PDF[Prevalence and knowledge of modifiable cardiovascular risk factors among patients of primary health care. Małopolska CArdiovascular Preventive Intervention Study (M-CAPRI)].
Przegl Lek
May 2018
Introduction: Cardiovascular diseases (CVD) are the main cause of death in Poland. The prevalence of CVD risk factors is regionally differentiated. Awareness of their presence in the population is crucial for identification of high-risk patients and implementation of appropriate preventive intervention.
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