Publications by authors named "Aleksandra Juszkiewicz"
Article Synopsis
- Giant cell arteritis (GCA) is a rare disease mainly found in older people, and it can cause serious problems like blindness if not treated quickly.
- Doctors now prefer using ultrasound instead of a biopsy to diagnose GCA because it's easier and safer, but it needs skilled technicians to work properly.
- A case of a 74-year-old woman shows how important it is to diagnose GCA quickly with ultrasound, as delays in treatment can lead to vision loss.
The aim of this study was the utilization of ground tea waste (GT) left after brewing black tea as a biofiller in natural rubber (NR) composites. Ionic liquids (ILs), i.e.
View Article and Find Full Text PDFIntroduction: Platelet-activating factor (PAF) has a direct role as a mediator in the pathogenesis of various disorders with an inflammatory component, including those with allergic aetiology. The peripheral blood concentration of PAF is dynamically regulated by plasma PAF acetylhydrolase (PAF-AH). Previous research suggest that low activity of plasma PAF-AH could be a predictive marker for increased severity of some types of allergic hypersensitivity reactions-especially anaphylaxis.
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- Rheumatoid arthritis (RA) is linked to higher cardiovascular risk, and this study explored genetic links between SNPs associated with atherosclerosis and subclinical atherosclerosis (SA) in RA patients.
- A total of 289 Polish RA patients were examined, with findings indicating that none of the 29 SNPs significantly correlated with SA, but a genetic risk score (GRS) was associated with SA in patients with early-stage RA.
- The results suggest that early RA patients may share genetic risk factors for SA like the general population, while those with long-standing RA might experience diminished influence from these genetic factors, potentially influenced by treatment with disease-modifying anti-rheumatic drugs (DMARDs).
Article Synopsis
- The study looked at how early rheumatoid arthritis (eRA) affects blood vessels compared to chronic RA patients and healthy people.
- They measured the thickness of carotid arteries and found that eRA patients had a faster increase in thickness after one year of treatment.
- The study concluded that eRA patients showed rapid changes in their blood vessels, especially if they had symptoms for a longer time and received less aggressive treatment.
Article Synopsis
- The study aims to compare preclinical atherosclerosis in diabetic vs. non-diabetic rheumatoid arthritis (RA) patients and evaluate factors influencing atherosclerosis as well as the effectiveness of ultrasound in detection.
- Researchers analyzed 42 non-diabetic RA patients, 42 diabetic RA patients, and 42 controls by measuring intima media thickness (IMT) and screening for atherosclerotic plaques in their arteries.
- Findings revealed that diabetic RA patients had a higher prevalence of atherosclerosis, indicated by greater plaque presence and IMT, while combining carotid and femoral ultrasound didn't enhance atherosclerosis detection compared to carotid ultrasound alone.
Article Synopsis
- * Researchers included 103 SLE patients and 95 control subjects, measuring IMT and screening for plaques in multiple arteries while correlating findings with various factors like age, gender, and SLE duration.
- * Results indicate strong associations between atherosclerosis and traditional cardiovascular risk factors, suggesting that continuous immunosuppressive treatment may improve IMT and reduce atherosclerosis risk in SLE patients.
Article Synopsis
- Rheumatoid arthritis (RA) increases the risk of cardiovascular disease, with a meta-analysis indicating higher intima media thickness (IMT) in RA patients, hinting at atherosclerosis progression.
- The study analyzed 317 RA patients and 111 controls to determine how various RA treatments affect IMT and atherosclerotic plaques.
- Results showed that higher doses of methotrexate (≥ 20 mg/wk), cyclosporine, or biologics lead to lower IMT and plaques compared to lower doses of MTX or other drugs, with no significant differences between the treatments.