Impact of the Frequency and Type of Procedures Performed in Nuclear Medicine Units on the Expected Radiological Hazard.

Nuclear medicine procedures play an important role in medical diagnostics and therapy. They are related to the use of ionizing radiation, which affects the radiological exposure of all of the persons involved in their performance. The goal of the study was to estimate the doses associated with the performance of various nuclear medicine procedures in order to optimize workload management.

The elemental changes occurring in the rat liver after exposure to PEG-coated iron oxide nanoparticles: total reflection x-ray fluorescence (TXRF) spectroscopy study.

The main goal of this study was to evaluate in vivo effects of low dose of PEG-coated magnetic iron oxide nanoparticles (IONPs) on the rat liver. The IONPs was intravenously injected into rats at a dose equaled to 0.03 mg of Fe per 1 kg of an animal body weight.

THE INFLUENCE OF PRE- AND POST-IRRADIATION ANNEALING ON LiF:Mg,Cu,P STABILITY.

The influence of pre- and post-irradiation annealing procedures on LiF:Mg,Cu,P (trade name MCP-N) thermoluminescent detector stability was investigated. The detectors were processed in four groups, undergoing complete or incomplete preparation cycles (containing pre- and/or post-irradiation annealing in various combinations). Each cycle was repeated 10 times.

Evaluation of spatial and seasonal radioactivity dose fluctuations in a Wierzchowska Górna limestone cave.

Measurements of the dose rate changes were carried out in order to assess seasonal and spatial radioactivity variations in the largest limestone cave of the Polish Jura Wierzchowska Górna. Thermoluminescence detectors, which were annealed, calibrated and protected against humidity were used. Measurements were repeated four times in 13 locations to observe possible changes.

Relationship between kinetics of albumin-bound bilirubin and water-soluble urea in extracorporeal blood purification.

Background: The purpose of the study was to examine the relationship between urea and conjugated bilirubin kinetics during extracorporeal liver support (ELS) therapy and to determine the dose of therapy for urea and conjugated bilirubin as markers for water-soluble and protein-bound solutes, respectively.

Methods: Kinetics of urea and bilirubin were described by standard two-compartment models with central clearance, constant intercompartment clearance, constant generation rate and constant volume. While the concentration of urea was assumed as equilibrated between compartments at the beginning of ELS therapy, the concentration of conjugated bilirubin between compartments was assumed to follow the partition of albumin between plasma and interstitial spaces.

Removal of bile acids by two different extracorporeal liver support systems in acute-on-chronic liver failure.

Acute-on-chronic liver failure (ACLF) is accompanied by marked intrahepatic cholestasis leading to accumulation of cytotoxic bile acids. Extracorporeal liver support systems efficiently remove bile acids, but their effect on bile acid composition in ACLF is unknown. The aim of the present study was to compare elimination of individual plasma bile acids by albumin dialysis (Molecular Adsorbents Recirculating System, MARS) and fractionated plasma separation (Prometheus).

Effect of extracorporeal liver support by MARS and Prometheus on serum cytokines in acute-on-chronic liver failure.

Introduction: Cytokines are believed to play an important role in acute-on-chronic liver failure (ACLF). Extracorporeal liver support systems may exert beneficial effects in ACLF via removal of cytokines. At present, two systems are commercially available, the Molecular Adsorbent Recirculating System (MARS) and Fractionated Plasma Separation, Adsorption and Dialysis (Prometheus).

Bilirubin kinetic modeling for quantification of extracorporeal liver support.

Background/aim: To provide a measure of treatment dose for extracorporeal liver support (ELS).

Methods: The kinetics of conjugated bilirubin were described by a two-compartment model (Vc, Vp) with central elimination (K) and constant generation rate (G). The transfer of solute between compartments was modeled by intercompartmental clearance (Kpc).

In vivo quantification of liver dialysis: comparison of albumin dialysis and fractionated plasma separation.

Background/aims: Artificial liver support represents a potentially useful option for the treatment of severe liver failure. A sufficient 'dose' might be crucial for such treatments to provide a survival benefit. The aim of this study was to compare in vivo efficiency and resulting delivered treatment dose of two commercially available devices that use different therapeutic principles: albumin dialysis (AD, MARS) and fractionated plasma separation (FPS, Prometheus).

Comparative diagnostic value of the breath test and the urine test with 14C-urea in the detection of the Helicobacter pylori infection.

Among 92 patients with chronic gastritis we conducted a synchronous diagnosis of the Helicobacter pylori (H. pylori) infection using a culture and a serological test (IFP), in conjunction with breath and urine tests involving (14)C-urea (BTU-C14 and UTU-C14). The infection was confirmed by isolation in 71 persons (77.