Publications by authors named "Aleksandra Gosk"
Article Synopsis
- - The presequence translocase TIM23 is crucial for transporting mitochondrial proteins into the matrix or inner membrane, with its core components being Tim23 and Tim17, but the details of the human TIM23 complex are not well understood.
- - Both TIMM17A and TIMM17B, the human equivalents of Tim17, are regulated by the prohibitin complex, which is necessary for stabilizing these variants.
- - The study highlights the role of OCIAD1 in working with prohibitins to protect the TIMM17A variant from degradation, suggesting an important regulatory relationship between OCIAD1, prohibitins, and the TIM23 complex.
Assembly of the dimeric complex III (CIII) in the mitochondrial inner membrane is an intricate process in which several accessory proteins are involved as assembly factors. Despite numerous studies, this process has yet to be fully understood. Here we report the identification of human OCIAD2 (ovarian carcinoma immunoreactive antigen-like protein 2) as an assembly factor for CIII.
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