Publications by authors named "Aleksandr V Iashnikov"
The synthetic availability and wide range of biological activity of hydrazides and hydrazones make them attractive subjects for investigation. In this study, we focused on synthesis of 2-methyl-5-nitro-6-phenylnicotinohydrazide-based hydrazones derived from the corresponding substituted aldehydes. The structure of the obtained compounds was studied using NMR spectroscopy and DFT calculations.
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- Bacterial communication through quorum sensing (QS) regulates their survival strategies, and plant-derived molecules can potentially disrupt this process to combat bacterial pathogens.
- Research found that oak bark extract (OBE) reduces QS signal production in Pectobacterium carotovorum, leading to decreased bacterial activity and increased resistance to soft-rot in potato tubers.
- Analysis revealed active compounds in OBE, and molecular docking studies suggest these could inhibit key bacterial proteins, highlighting oak bark's promise for bacterial control in agriculture.