Synopsis of recent research by authors named "Aleksandr Shavrin"
- Aleksandr Shavrin's research focuses on developing novel radiotracers for non-invasive molecular imaging techniques, particularly using positron emission tomography (PET) to study the expression and activity of epigenetic regulators like Sirtuin proteins and the epidermal growth factor receptor (EGFR) in various diseases.
- His work has resulted in the synthesis of substrate-type radiotracers that allow for the real-time monitoring of SIRT1 and SIRT2, as well as the development and evaluation of radiotracers targeting mutated EGFR in non-small cell lung carcinomas, addressing significant barriers in current diagnostic approaches.
- Shavrin's studies highlight the utility of advanced imaging techniques for early cancer detection and treatment stratification, particularly in pancreatic cancer and lung carcinomas, showcasing the potential for personalized therapies based on molecular imaging biomarkers.