Publications by authors named "Aleksandr Sarachakov"
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Synopsis of recent research by authors named "Aleksandr Sarachakov"
- Aleksandr Sarachakov's recent research emphasizes the spatial anatomy of hematopoiesis in the human bone marrow, addressing gaps in knowledge due to previous technical limitations in human studies compared to preclinical models.
- His study employs an innovative end-to-end pipeline combining multiparameter whole tissue staining, in situ imaging at single-cell resolution, and AI-based digital analysis to explore the topographic changes in hematopoiesis linked to aging.
- Published in the journal "Blood," the findings reveal significant alterations in the hematopoietic topography of disease-free human samples as they age, contributing valuable insights into the biological processes underlying hematopoiesis.