Publications by authors named "Aleksandr Boytsov"
Article Synopsis
- Human iPSC cell line FAMRCi009-A was created from a patient with restrictive cardiomyopathy and a specific genetic variant (FLNC p.Val2264Met).
- The cell line was generated using non-integrative Sendai viruses, resulting in iPSCs that have a normal karyotype and express key pluripotency markers.
- These iPSCs demonstrated the ability to differentiate into three germ layers in vitro, making them valuable for studying filaminopathies in greater detail.
Human iPSC cell line FAMRCi010-A was generated from a patient with restrictive cardiomyopathy carrying FLNC p.Gly2011Arg genetic variant. Patient-specific peripheral blood mononuclear cells were reprogrammed using non-integrative Sendai viruses containing OCT4, SOX2, KLF4, and CMYC.
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