Publications by authors named "Aleksandr A Miroshnikov"
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Synopsis of recent research by authors named "Aleksandr A Miroshnikov"
- Recent research by Aleksandr A Miroshnikov focuses on the impact of single-nucleotide polymorphisms (SNPs) on the enzymatic activity of DNA polymerase β (Polβ), crucial for genome stability and base excision repair mechanisms.
- His study titled "SNP-Associated Substitutions of Amino Acid Residues in the dNTP Selection Subdomain Decrease Polβ Polymerase Activity" highlights how specific SNPs can alter amino acid residues in Polβ, potentially reducing its functionality.
- The findings emphasize the significance of understanding genetic variations in Polβ, as they could influence the efficacy of DNA repair processes and, consequently, genomic integrity.
