Publications by authors named "Aleksandar Tomasevic"

The present research evaluated evidence for structural and convergent validity and measurement invariance across gender of the Aspects of Identity Questionnaire-IV (AIQ-IV), which is designed to measure four identity orientations: Personal, Relational, Public, and Collective. We recruited two independent samples of Serbian adolescents aged 15-19 years ( = 436, = 452). Both exploratory structural equation modeling (ESEM) and confirmatory factor analyses (CFA) were applied to examine the factor structure of the AIQ-IV.

View Article and Find Full Text PDF

(1) Background: This study aimed to develop a machine learning model based on radiomics of pretreatment magnetic resonance imaging (MRI) 3D T2W contrast sequence scans combined with clinical parameters (CP) to predict neoadjuvant chemoradiotherapy (nCRT) response in patients with locally advanced rectal carcinoma (LARC). The study also assessed the impact of radiomics dimensionality on predictive performance. (2) Methods: Seventy-five patients were prospectively enrolled with clinicopathologically confirmed LARC and nCRT before surgery.

View Article and Find Full Text PDF

Research into the role of identity orientations (the relative importance an individual places on different personal and social attributes and characteristics when defining her or his identity) in adolescent mental health is extremely limited. Furthermore, the potential mechanisms that might explain the associations between identity orientations and adolescent mental health are poorly understood. This study protocol describes a one-year longitudinal study across three time points to be initiated with the purpose of investigating the mediating role of basic psychological needs satisfaction and frustration in the relationship between identity orientations and various mental health indicators in adolescence.

View Article and Find Full Text PDF

During radiotherapy treatment for cervical cancer, up to 84% of patients exhibit some form of acute radiation toxicity (ART). The primary aim of this clinical study is to determine the impact of angiotensin-converting enzyme (ACE) inhibitors, β-blockers and other risk factors such as the patient's anatomical characteristics on ART emergence in patients with locally advanced cervical cancer treated by chemoradiotherapy. This is a combination of two nested case-control studies within the cohort of patients with locally advanced cervical cancer based on the analysis of potential risk factors for the onset of ART in patients treated with 3D conformal radiotherapy (3D-CRT) and 2D conventional radiotherapy (2D-RT), prospectively followed up from January 2017 to September 2018 in a tertiary care hospital.

View Article and Find Full Text PDF

Purpose: To analyze the dose distribution achieved during 2D radiography-based brachytherapy (BRT) planning, by using a 3D MRI-based BRT replanning evaluation, in patients with advanced cervical carcinoma, treated with definitive concomitant chemoradiation (CCRT).

Methods: The curative CCRT was applied to 30 patients with advanced cervical carcinoma. For each patient, 2D radiography-based planning and a 3D MRI-based BRT replanning were performed.

View Article and Find Full Text PDF

Purpose: The toxicity of postoperative radiotherapy for cervical cancer affects patients' quality of life. We evaluated acute toxicity in postoperative intensity-modulated radiotherapy (IMRT) and three-dimensional conformal radiotherapy (3DCRT) as well as the influence of dosimetric parameters and concomitant chemotherapy.

Methods: A total of 45 patients with early operable cervical cancer underwent postoperative IMRT with 40-45 Gy.

View Article and Find Full Text PDF
Article Synopsis
  • - The study compared intensity-modulated radiotherapy (IMRT) to three-dimensional conformal radiotherapy (3DCRT) in the postoperative treatment of cervical cancer, focusing on dosimetric parameters for target volumes and organs at risk (OARs).
  • - After randomizing 95 cervical cancer patients into two treatment groups (IMRT and 3DCRT), results indicated that IMRT provided better conformity and dosimetric outcomes, especially in terms of protecting the bladder, rectum, and bowel from high doses of radiation.
  • - The conclusion is that IMRT offers better sparing of OARs while maintaining adequate coverage of target volumes, which could lead to improved quality of life for patients with cervical cancer who have
View Article and Find Full Text PDF

Introduction: To define indications for adjuvant radiotherapy in patients with endometrial cancer, the risk groups have been established according to clinical and pathological prognostic factors. The purpose was to determine precise criteria for adjuvant radiotherapy and identify patients with increased risk for disease relapse who may benefit from postoperative radiotherapy, with an acceptable level of toxicity.

Materials And Methods: A retrospective study was conducted at the Department of Oncology and Radiology, Kragujevac, during a 5-year period.

View Article and Find Full Text PDF

Purpose: To investigate the influence of the vaginal packing volume on the registered dose parameters evaluated by radiography (2D) and computed tomography (CT) (3D) based brachytherapy planning in cervical cancer patients treated with postoperative radiotherapy.

Methods: The postoperative radiotherapy was performed in 40 cervical cancer patients with increased risk for disease relapse. Both, radiography and CT based brachytherapy planning were done in all patients.

View Article and Find Full Text PDF