[Retinoprotective effects of Retinalamin studied in an experimental model of photochemical damage to rabbit retinas].

Unlabelled: Purpose - to investigate functional and morphological effects of peptide bioregulator (Retinalamin) in modeling of photochemical damage to rabbit retina.

Material And Methods: The study was conducted on 36 rabbits (72 eyes) randomized into 4 equal groups: two experimental groups received parabulbar injections of Retinalamin («Geropharm», Russia) in each eye in dosages of 0.25 mg/kg in a course of 10 days starting from day 1 and day 10 of the experiment, respectively, and two control groups that received injections of normal solution with the same regimen.

Modeling of Retinal Degeneration.

We developed a model of retinal degeneration in rabbits based on exposure to light with a wavelength of 405 nm. This model allows reproducing structural and functional disorders in the central parts of the retina, including primarily degeneration of the outer layers of the retina (retinal pigment epithelium and layer of photoreceptor cells), and is designed to study the mechanisms of formation, progression and effectiveness of new drugs and methods of treatment of degenerative diseases of the retina.

[Multifocal electroretinography in the study of focal and diffuse damage to the rabbit retina].

Purpose: To evaluate the possibility of using the system "Neuro-ERG" (with a module for multifocal ERG) in the study of focal and diffuse pathology in laboratory animals (rabbits).

Material And Methods: Focal retinal damage was modelled in 5 eyes of 5 rabbits by singular laser pulses (532 nm, 100 ms, power 30, 60, 100, 150 and 200 mW) and diffuse retinal damage was modelled in 5 eyes of 5 rabbits by exposure to polychromatic light for 14 days (9500 lm, 6400 K, 230 mW/cm2, 8 h/day). The pair of eyes and areas of intact retina in the eyes with focal retinal damage were used for control.

[Acute ocular lesions after exposure to electromagnetic radiation of ultrahigh frequency (an experimental study)].

Purpose: To investigate the clinical and morphological manifestations of ocular lesions resulting from acute exposure to microwave radiation (MR).

Material And Methods: Twenty-four rabbits were included in the study and divided into four equal groups according to MR exposure time (15, 30, 45, 60 s). The right eyes of rabbits were exposed to MR of 3.

[Mirizzi syndrome management (in Russian only)].

Aim: To assess an effectiveness of complex preoperative diagnosis, conservative treatment, minimally invasive biliary decompression for Mirizzi syndrome and to analyze surgical outcomes depending on the effectiveness of minimally invasive biliary decompression.

Material And Methods: There were 67 patients with Mirizzi syndrome aged 27-96 years (mean age -64.8 years).

The Effect of Electromagnetic Fields of Extremely Low Frequency 30 Hz on Rat Ovaries.

We studied the effects of extremely low-frequency electromagnetic field on the ovaries in rats. The female rats were exposed to a 30 Hz sinusoidal magnetic field of 4 kA/m for 2 h per day for a period of 10 weeks, including the period of embryonic development. After the exposure, the duration of the estrous cycle and serum levels of luteinizing hormone, follicle stimulating hormone, progesterone, and estradiol E2 were measured in different phases of the estrous cycle and morphological changes in the ovaries were evaluated.

A case of a tumor-like condition in the optic nerve head of a pig.

A tumor-like condition of the optic nerve head of unknown etiology was found in a domestic pig. Clinical and histological manifestations suggest that the unusual tumor-like condition is probably a variant of proliferative optic neuropathy caused by unknown nonspecific damage (perhaps trauma), which was received earlier.

[Intussusception followed by intestinal obstruction in adults].

Aim: To evaluate the effectiveness of complex preoperative diagnostics and medication of intussusception followed by intestinal obstruction in adults with the choice of surgical repair and analysis of the outcomes depending on the causes of intussusception.

Material And Methods: 15 intussusception patients aged 19 - 86 years were enrolled. Mean age was 52.

[Diagnostics and surgical treatment of the tumor obturative intestinal obstruction].

The study summarize the results of diagnostics and treatment of 536 patients aged 37-97 years with colon cancer stage II-IV, complicated by bowel obstruction. Patients with subcompensated and decompensated bowel obstruction prevailed. The dependence of the clinical picture from the tumor localization and the severity of the obstruction were identified.

[The effectiveness of intraocular delivery of 5-fluoroquinolones for prophylaxis of intraocular infection].

The authors examined the possibility of the usage of ionic soft contact lenses for intraocular delivery of antibiotics for prophylaxis of intraocular infection in open combat trauma of the eyes during the stages of medical evacuation to the local military conflicts, as well as to the hospital before elective surgery. It is proved high efficiency lens, moxifloxacin and levofloxacin saturated to prevent inflammatory complications of the eyes.

[Extended, combined, and concurrent surgery in patients with neoplastic obturation large bowel obstruction].

The study included 552 patients (mean age 68.9 +/- 1.0 years) with neoplastic obturation large bowel obstruction (NOLBO).

[Valvular pyloroplasty in the treatment of pyloroduodenal ulcers].

Original method of treatment of complicated pyloroduodenal ulcers is proposed. The results of different organ-saving operations in complicated pyloroduodenal ulcers were analyzed in 136 patients aged from 15 to 89 years. Evaluation of the results was based on the data obtained during study of secretory and motor-evacuatory function of the stomach, state of gastric and duodenal mucous membrane, degree of duodenogastric reflux.